Administration of ZOLADEX SafeSystem

ZOLADEX SafeSystem’ provides ready to use, one-step delivery

'ZOLADEX SafeSystem’ 3.6mg and ‘ZOLADEX SafeSystem’ 10.8mg are provided as convenient, ready-mixed, ready-to-use sterile syringe systems that ensure a consistent volume of depot injection time after time.


Fig 1. ‘ZOLADEX SafeSystem’ 3.6mg and ‘ZOLADEX SafeSystem’ 10.8mg


‘ZOLADEX SafeSystem’ syringes are fitted with a needle that is specially designed to optimise ZOLADEX administration.

'ZOLADEX SafeSystem’ is provided with a protective shield, to reduce the risk of needle stick injuries.

'ZOLADEX SafeSystem' - reduces risk of needle stick injury

ZOLADEX Safe System Video (2051kb)

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‘ZOLADEX SafeSystem’ is injected subcutaneously into the anterior abdominal wall below the navel according to the methods described below.

ZOLADEX SafeSystem	Click image to enlarge
1 Put the patient in a comfortable position with the upper part of the body slightly raised Swab an area of the abdominal wall below the navel line Prepare the area for injection according to local guidelines
2 Examine the foil pouch and syringe for damage
3 Remove the syringe and check that at least part of the ZOLADEX depot is visible As ZOLADEX is not a liquid injection do not try and remove air bubbles as this may displace the depot
4 Pull the plastic safety tab away from the syringe and discard Remove needle cover
5 Hold the syringe around the barrel Pinch the abdominal skin and insert the point at an angle of 30 to 45 degrees to the skin with the needle opening facing upwards Continue to insert into subcutaneous tissue until the protective shield touches the patient skin
6 To administer the ZOLADEX depot, depress the plunger until you can depress it no further. This will activate the protective shield. You may hear a 'click' and will feel the protective shield automatically begin to slide to cover the needle If the plunger is not FULLY depressed, the protective shield will NOT activate
7 Withdraw the needle and allow the protective shield to slide and cover the needle
8 Dispose of the syringe in an approved sharps collector